HTA project outputs
lease see HTA projects below which have had papers accepted and published in well-renowned journals.
Project title: A 1-year follow-on study from a randomised, head-to-head, multicentre, open-label study of two pandemic influenza vaccines in children (link to project page)
Article title: H1N1 Antibody Persistence 1 Year After Immunization With an Adjuvanted or Whole-Virion Pandemic Vaccine and Immunogenicity and Reactogenicity of Subsequent Seasonal Influenza Vaccine: A Multicenter Follow-on Study Clinical Infectious Diseases 2012; doi: 10.1093/cid/cir905 (link to article)
Project title: Weight Loss Maintenance in Adults: A 3 arm individually randomised controlled trial to evaluate the impact of a 12-month multi-component intervention and less intensive version compared to a control on weight loss maintenance in obese adults (link to project page)
Article title: Uncertainties page: What is the most effective way to maintain weight loss in adults? BMJ 2011;343:d8042 (link to article)
Project title: The clinical and cost effectiveness of exercise referral schemes: a systematic review and economic evaluation (link to project page)
Article title: Effect of exercise referral schemes in primary care on physical activity and improving health outcomes: systematic review and meta-analysis BMJ 2011; 343:d6462 (link to article)
Project title: The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department (link to project page)
Article title: Very early diagnosis of chest pain by point-of-care testing: comparison of the diagnostic efficiency of a panel of cardiac biomarkers compared with troponin measurement alone in the RATPAC trial Heart 2011; 10:1136 (link to article)
Project title: Randomised controlled trial of continuous subcutaneous insulin infusion compared to multiple daily injection regimens in children and young people at diagnosis of type I diabetes mellitus (link to project page)
Article title: What is the best way to deliver subcutaneous insulin to infants, children, and young people with type 1 diabetes mellitus? BMJ 2011; 343:d5221 (link to article)
Project title: Anglo-Danish-Dutch study of Intensive Treatment of people with Newly diagnosed diabetes in primary care (ADDITION) - effects on cardiovascular events at five years (link to project page)
Article title: Cardiovascular outcomes in the ADDITION-Europe study: a five-year cluster-randomised controlled trial of multifactorial therapy in individuals with screen-detected type 2 diabetes The Lancet 2011,378(9786)156-167 (link to article)
Project title: The clinical and cost effectiveness of etanercept, infliximab and adalimumab - psoriatic arthritis (link to project page)
Article title: Modelling the cost-effectiveness of biologic treatments for psoriatic arthritis Rheumatology Journal 2011, 50(4):39-47 (link to article)
Project title: Antidepressant Controlled Trial of Negative symptoms in Schizophrenia (ACTIONS) (link to project page)
Article title: Do antidepressants improve negative symptoms in schizophrenia? BMJ 2011; 342:d3371 (link to article)
Project title: Pulse oximetry as a screening test for congenital heart disease in newborn babies (link to project page)
Article title: Pulse oximetry screening for congenital heart defects in newborn infants (PulseOx): a test accuracy study The Lancet 2011;doi:10.1016 (link to article)
Project title: A study of the safety and harms of antidepressant drugs for older people: a cohort study using a large primary care database (link to project page)
Article title: Antidepressant use and risk of adverse outcomes in older people: population based cohort study BMJ 2011;343:d4551 (link to article)
Project title: HTA study of antidepressants for depression in dementia - a definitive multicentre pragmatic randomised controlled trial of clinical and cost effectiveness (HTA-SADD) (link to project page)
Article title: Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial The Lancet 2011, doi:10.1016 (link to article)
Project title: Conservative treatment for urinary incontinence in Men After Prostate Surgery (MAPS): two parallel randomised controlled trials (link to project page)
Article title: Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials. The Lancet 2011, 6736(11)60751-4 (link to article)
Project title: Anglo-Danish-Dutch study of Intensive Treatment of people with Newly diagnosed diabetes in primary care (ADDITION) - effects on cardiovascular events at five years (link to project page)
Article title: Cardiovascular outcomes in the ADDITION-Europe study: a five-year cluster-randomised controlled trial of multifactorial therapy in individuals with screen-detected type 2 diabetes. The Lancet 2011, 378(9786)156-167 (link to article)
Project title: UK Lung Cancer Screening Trial (UKLS) - Feasibility study and protocol development (link to project page)
Article title: CT screening for lung cancer in the UK: position statement by UKLS investigators following the NLST report Thorax doi:10.1136/thoraxjnl-2011-200351 (link to article)
Project title: Influenza A/H1N1v in pregnancy: an investigation of the characteristics and management of affected women and the relationship to pregnancy outcomes for mother and infant. (link to project page)
Article title: Perinatal outcomes after maternal 2009/H1N1 infection: national cohort study. BMJ 2011; 342:d3214 (link to article)
Project title: A pragmatic single-blind RCT and health economic evaluation of leukotriene receptor antagonists in primary care at steps two and three of the national asthma guidelines (ELEVATE) (link to project page)
Article title: Leukotriene Antagonists as First-Line or Add-on Asthma-Controller Therapy. New England Journal of Medicine 2011; 364:1695-1707 (link to article)
Project title: VenUS III - Venous Ulcer Studies III: ultrasound for venous leg ulcers (link to project page)
Article title: Economic evaluation of a randomized controlled trial of ultrasound therapy for hard-to-heal venous leg ulcers. British Journal of Surgery, 2011, Doi: 10.1002/bjs.7501 (link to article)
Project title: First trimester progesterone therapy in women with a history of unexplained recurrent miscarriages: A randomised, double-blind, placebo-controlled, multi-centre trial [The PROMISE (PROgesterone in recurrent MIScarriage) Trial] (link to project page)
Article title: Does first trimester progesterone prophylaxis increase the live birth rate in women with unexplained recurrent miscarriages? BMJ, 2011; 342:d1914 (link to article)
Project title: The growth and rupture rate of small abdominal aortic aneurysms: implications for population re-screening intervals (link to project page)
Article title: Systematic review and meta-analysis of growth rates of small abdominal aortic aneurysms. British Journal of Surgery 2011; 98(5):2-11 (link to article)
Project title: The growth and rupture rate of small abdominal aortic aneurysms: implications for population re-screening intervals (link to project page)
Article title: Rupture rates of small abdominal aortic aneurysms: a systematic review of the literature. European Journal of and Endovascular Surgery 2011; 41(1):2-10 (link to article)
Project title: CRASH2 Trial, a large randomised placebo controlled trial among trauma patients with significant haemorrhage of the effects of an antifibrinolytic treatment on death and transfusion requirement (link to project page)
Article title: The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. The Lancet 2011; 377(9771):1096-1101 (link to article)
If you are currently managing an HTA project and would like to submit a paper and/or present your work, please complete and return the following form: HTA project outputs (pdf, 328 KB)
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