Research type:
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NICE Technology Assessment Report (TAR) |
Title (lead author) etc:
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Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation (Takeda) 237 pages, Volume 14, number 42 |
Link to NICE guidance page
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DOI
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10.3310/hta14420 |
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View full text in pdf format (1823 KB)
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Headline: |
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox-containing gene deficiency, and those who were small for gestational age, than for untreated children. However, treatment was considered to be cost-effective at a willingness to pay threshold of £20,000–30,000 per quality-adjusted life-year gained only for children with GHD, although the analysis is subject to a range of important uncertainties |
This report should be referenced as follows: |
Takeda A, Cooper K, Bird A, Baxter L, Frampton G, et al. Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation. Health Technol Assess
2010;14(42).
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Project ref: |
08/51/01 |
Original project title: |
Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation |
Chief Investigator: |
Southampton Health Technology Assessment Centre (SHTAC), University of Southampton
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Start Date: |
September 2008 |
Date of publication in HTA journal series |
September 2010
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Cost: |
This project was commissioned by the HTA programme on behalf of the National Institute for Health and Clinical Excellence on a call-off contract basis |
Project Protocol: |
Project protocol not available
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Printed copies of this title despatched:
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190 (Figures relate to the previous calendar month) |
URL of this page: |
http://www.hta.ac.uk/1755 |
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