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Details of HTA journal title

Last updated: 31 August 2010 - Next update due: 7 September 2010

Research type:

HTA Technology Assessment Report 

Title (lead author) etc:

Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional hemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation  (McLeod) 144 pages, Volume 13, number 1

DOI

10.3310/hta13010
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Headline:

Study found that, in the short term, there is little clinical difference between deferasirox, deferoxamine and deferiprone in terms of removing iron from the blood and liver, and that deferasirox may be cost-effective compared with deferoxamine in patients with beta-thalassaemia and sickle cell disease but is unlikely to be cost-effective compared with deferiprone 

This report should be referenced as follows:

McLeod C, Fleeman N, Kirkham J, Bagust A, Boland A, Chu P, et al. Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional hemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation. Health Technol Assess 2009;13(1).

Project ref:

06/12/01 

Original project title:

Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional hemosiderosis) in patients suffering with chronic anaemia 

Chief Investigator:

Liverpool Reviews and Implementation Group (LRIG), University of Liverpool  

Start Date:

May 2007  

Date of publication in HTA journal series

January 2009

Cost:

 This project was commissioned by the HTA programme on a call-off contract basis.

NRR* number, if applicable:

N0484193512 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive.

Project Protocol:

Project protocol (pdf format, 323 kbytes)

Printed copies of this title despatched:

112 (Figures relate to the previous calendar month)

Downloads/Views of electronic version from website:

24928 (Figures are cumulative.) Last updated 27th July 2010.

URL of this page:

http://www.hta.ac.uk/1632

Outputs from this project

  • McLeod C; Fleeman N; Kirkham J; Bagust A; Boland A; Chu P; Dickson R; Dundar Y; Greenhalgh J; Modell B; Olujohungbe A; Telfer P; Walley T.. Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation.. Health Technology Assessment. 2009; 13(1):1-144..
Tue, 31 Aug 2010 16:14:06 +0100

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