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Details of HTA journal title

Last updated: 31 August 2010 - Next update due: 7 September 2010

Research type:	Secondary Research (e.g. systematic review)
Title (lead author) etc:	A comparison of the cost-effectiveness of five strategies for the prevention of non-steroidal anti-inflammatory drug-induced gastrointestinal toxicity: a systematic review with economic modelling (Brown) 202 pages, Volume 10, number 38
DOI	10.3310/hta10380
View/print executive summary View/print abstract View full text in pdf format (1492 KB) View separate 223 page appendix in pdf format (807 KB) The appendix is only available electronically. It is not available in the printed version. Buy a printed version of this title - cost £20.00 each. [How to order] This title is available on our CD-ROM of the journal. Order a CD-ROM - free of charge worldwide. Go to our correspondence page to comment on this publication
Outputs in journals arising from this project
Headline:	Study suggests the most cost-effective strategies for avoiding endoscopic ulcers in patients requiring long-term non-steroidal anti-inflammatory drugs (NSAIDs) are Cox-1 NSAID plus histamine-2 receptor antagonist for low-risk patients and Cox-1 NSAID plus proton pump inhibitors for high-risk patients.
Project ref:	01/40/02
Original project title:	A comparison of the cost-effectiveness of four strategies for the prevention of non-steroidal anti-inflammatory drug (NSAID) induced gastrointestinal toxicity - a systematic review with economic modelling
Chief Investigator:	Professor Deborah Pauline Mary Symmons, Prof Rheumatology and Musculoskeletal Epidemiology, ARC Epidemiology Unit, University of Manchester
Start Date:	June 2002
Date of publication in HTA journal series	October 2006
Cost:	£80,308
MeSH* index primary terms:	ANTI-INLAMMATORY-AGENTS-NON-STEROIDAL Q-adverse-effects; GASTROINTESTINAL-DISEASES Q-chemically-induced (* = Medical Subject Headings)
MeSH* index secondary terms:	HUMAN; RANDOMIZED-CONTROLLED-TRIAL; CLINICAL-TRIAL; QUALITY-OF-LIFE; COST-BENEFIT-ANALYSIS (* = Medical Subject Headings)
NRR* number, if applicable:	N0484112113 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive.
Project Protocol:	Project protocol not available
Printed copies of this title despatched:	113 (Figures relate to the previous calendar month)
Downloads/Views of electronic version from website:	63593 (Figures are cumulative.) Last updated 27th July 2010.
URL of this page:	http://www.hta.ac.uk/1300