Details of HTA journal title
Research type: |
Secondary Research (e.g. systematic review) |
Title (lead author) etc: |
A comparison of the cost-effectiveness of five strategies for the prevention of non-steroidal anti-inflammatory drug-induced gastrointestinal toxicity: a systematic review with economic modelling (Brown) 202 pages, Volume 10, number 38 |
DOI |
10.3310/hta10380 |
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Headline: |
Study suggests the most cost-effective strategies for avoiding endoscopic ulcers in patients requiring long-term non-steroidal anti-inflammatory drugs (NSAIDs) are Cox-1 NSAID plus histamine-2 receptor antagonist for low-risk patients and Cox-1 NSAID plus proton pump inhibitors for high-risk patients. |
Project ref: |
01/40/02 |
Original project title: |
A comparison of the cost-effectiveness of four strategies for the prevention of non-steroidal anti-inflammatory drug (NSAID) induced gastrointestinal toxicity - a systematic review with economic modelling |
Chief Investigator: |
Professor Deborah Pauline Mary Symmons, Prof Rheumatology and Musculoskeletal Epidemiology, ARC Epidemiology Unit, University of Manchester |
Start Date: |
June 2002 |
Date of publication in HTA journal series |
October 2006 |
Cost: |
£80,308 |
MeSH* index primary terms: |
ANTI-INLAMMATORY-AGENTS-NON-STEROIDAL Q-adverse-effects; GASTROINTESTINAL-DISEASES Q-chemically-induced (* = Medical Subject Headings) |
MeSH* index secondary terms: |
HUMAN; RANDOMIZED-CONTROLLED-TRIAL; CLINICAL-TRIAL; QUALITY-OF-LIFE; COST-BENEFIT-ANALYSIS (* = Medical Subject Headings) |
NRR* number, if applicable: |
N0484112113 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive. |
Project Protocol: |
Project protocol not available |
Printed copies of this title despatched: |
113 (Figures relate to the previous calendar month) |
URL of this page: |
http://www.hta.ac.uk/1300 |
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