Details of HTA journal title
Last updated: 9 March 2010 - Next update due: 16 March 2010
Research type: |
Secondary Research (e.g. systematic review) |
Title (lead author) etc: |
Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis (Knowles) 168 pages, Volume 9, number 44 |
DOI |
10.3310/hta9440 |
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Outputs in journals arising from this project
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Headline: |
Study findings suggest that the current programme to detect congenital heart defects through newborn screening performs poorly and lacks monitoring of quality assurance, performance management and longer term outcomes. Pulse oximetry is a promising alternative newborn screening strategy and requires further evaluation. |
Project ref: |
99/45/01 |
Original project title: |
Screening in the first year of life for congenital heart disease: review and cost-effectiveness analysis |
Chief Investigator: |
Professor Carol Dezateux, Professor of Paediatric Epidemiology, Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health |
Start Date: |
March 2001 |
Publication date: |
November 2005 |
Cost: |
£59,749 |
MeSH* index primary terms: |
NEONATAL-SCREENING Q-economics; HEART-DEFECTS-CONGENITAL Q-diagnosis (* = Medical Subject Headings) |
MeSH* index secondary terms: |
HUMAN; REVIEW; COST-BENEFIT-ANALYSIS; INFANT-NEWBORN; INFANT (* = Medical Subject Headings) |
NRR* number, if applicable: |
N0484094186 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive. |
Project Protocol: |
Project protocol not available |
Printed copies of this title despatched: |
115 (Figures relate to the previous calendar month) |
Downloads/Views of electronic version from website: |
55159 (Figures are cumulative.) Last updated 12th January 2010. |
URL of this page: |
http://www.hta.ac.uk/1207 |
Outputs from this project
- Knowles, RL; Griebsch, I; Bull, C; Brown, J; Wren, C; Dezateux, C. Quality-of-life and congenital heart defects: comparing parent and professional values. Arch. Dis. Child. Published on line 31 May 2006 doi:10.1136/adc.2005.075606.
- Griebsch, I; Knowles, RL; Brown, J; Bull, C; Wren, C; Dezateux, CA.. Comparing the clinical and economic effects of clinical examination, pulse oximetry, and echocardiography in newborn screening for congenital heart defects: a probabilistic cost-effectiveness model and value of information analysis.. International Journal of Technology Assessment in Health Care, Volume 23, issue 2, pp 192-204.
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