Details of HTA journal title
Last updated: 31 August 2010 - Next update due: 7 September 2010
Research type: |
Primary Research (e.g. trial) |
Title (lead author) etc: |
ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screening (Kitchener) 150 pages, Volume 13, number 51 |
DOI |
10.3310/hta13510 |
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Outputs in journals arising from this project
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Headline: |
This study found that it would not be either effective or cost-effective to screen with cytology and human papillomavirus (HPV) combined when compared with liquid-based cytology alone. HPV testing, either as triage or as initial test triaged by cytology, would be cheaper than cytology without HPV testing |
Special notes |
This project is being continued under Project ref: 98/04/99. |
This report should be referenced as follows: |
Kitchener H C, Almonte M, Gilham C, Dowie R, Stoykova B, Sargent A, et al. ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screening. Health Technol Assess 2009;13(51). |
Project ref: |
98/04/64 |
Original project title: |
A randomised trial of human papilloma virus testing in primary cervical screening (ARTISTIC) |
Chief Investigator: |
Professor Henry Charles Kitchener, Professor of Gynaecological Oncology, Academic Unit of Obstetrics and Gynaecology, University of Manchester |
Start Date: |
June 2001 |
Date of publication in HTA journal series |
November 2009 |
Cost: |
£1,186,679 |
MeSH* index primary terms: |
PAPILLOMAVIRUS-HUMAN; PAPOVAVIRIDAE-INFECTIONS Q-diagnosis; TUMOR-VIRUS-INFECTIONS Q-diagnosis; MASS-SCREENING Q-economics (* = Medical Subject Headings) |
MeSH* index secondary terms: |
HUMAN; FEMALE; ADULT; MIDDLE-AGE; COLPOSCOPY; COSTS-AND-COST-ANALYSIS; TRUTH-DISCLOSURE; ADAPTATION-PSYCHOLOGICAL (* = Medical Subject Headings) |
ISRCTN* number: | ISRCTN 25417821 (*International Standard Randomised Controlled Trial Number) URL of this project on the Controlled Trials Website: http://www.controlled-trials.com/ISRCTN25417821 |
NRR* number, if applicable: |
N0484087730 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive. |
Project Protocol: |
Project protocol (pdf format, 173 kbytes) |
Printed copies of this title despatched: |
110 (Figures relate to the previous calendar month) |
Downloads/Views of electronic version from website: |
12636 (Figures are cumulative.) Last updated 27th July 2010. |
URL of this page: |
http://www.hta.ac.uk/1162 |
Outputs from this project
- Dowie, R; Stoykova, B; Crawford, D; Desai, M; Mather, J; Morgan, K; Shirt, M. Liquid-based cytology can improve efficiency of cervical smear readers: evidence from timing suveys in two NHS cytology laboratories. Cytopathology 2005, 16, 1-8.
- Dowie, R; Stoykova, B; Desai, M. Assessing the wellbeing of cytoscreeners: experience in two NHS cytology laboratories. Cytopathology 2006, 17, 366-373.
- Kitchener, HC; Almonte, M; Wheeler, P; Desai, M; Gilham, C; Baily, A; Sargent, A; Peto, J. HPV testing in routine cervical screening: cross sectional data from the ARTISTIC trial. Br J Cancer. 2006 Jul 3;95(1):56-61. Epub 2006 Jun 13..
- Sargent, A; Bailey, A; Almonte, M; Turner, A; Thomson, C; Peto, J; Desai, M; Mather, J; Moss, S; Roberts, C, Kitchener, HC; ARTISTIC Study Group. Prevalence of type-specific HPV infection by age and grade of cervical cytology: data from the ARTISTIC trial. British Journal of Cancer, Vol 98, issue 10, 1704 - 1709.
- Sargent, A; Bailey, A; Almonte, M; Turner, A; Thomson, C; Peto, J; Desai, M; Mather, J; Moss, S; Roberts, C; Kitchener, HC;. Prevalence of type-specific HPV infection by age and grade of cytology:Data from the ARTISTIC trial. British Journal of Cancer,.
- Kitchener, H; Almonte, M; Thomson, C; Wheeler, P; Sargent, A; Stoykova, B; Gilham, C; Baysson, H; Roberts, C; Dowie, R; Desai, M; Mather, J; Bailey, A; Turner, A; Peto, J; Moss, S. HPV testing in combination with liquid-based cytology in primary cervical screening (ARTISTIC): a randomised controlled trial. The Lancet Oncology, Volume 10, Issue 7, Pages 672 - 682, July 2009.
- Sargent, A; Bailey, A; Turner, A; Almonte, M; Baysson, H; Peto, J; Roberts, C; Thomson, C; Desai, M; Mather, J; Kitchener, H. Optimal cut-off for a postitive Hybrid Caputure 2 test - Data from the ARTISTIC trial. Journal of Clinical Microbiology,2010:48(2)554-8.
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