Research in progress

Last updated: 1 February 2012 - Next update due: 8 February 2012

Projects are listed in order of intended publication date, soonest first. Followed by completed projects that do not require publication.

• Adalimumab for the treatment of moderate to severe psoriatic arthritis. HTA Ref: 06/54/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2009.
  
  
• Natalizumab for multiple sclerosis. HTA Ref: 06/65/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2009.
  
  
• Mifamurtide for osteosarcoma. HTA Ref: 08/77/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2009.
  
  
• Pemetrexed for the treatment of relapsed non-small cell lung cancer. HTA Ref: 06/24/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2010.
  
  
• Tocilizumab for the treatment of rheumatoid arthritis. HTA Ref: 08/90/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2010.
  
  
• Abatacept for the treatment of refractory rheumatoid arthritis. HTA Ref: 06/52/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2011.
  
  
• Erlotinib monotherapy for the maintenance treatment of non-small cell lung cancer after previous platinum-containing therapy. HTA Ref: 08/200/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2011.
  
  
• Aripiprazole for the treatment of schizophrenia in adolescents (aged 15-17 years). HTA Ref: 09/97/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2011.
  
  
• Golimumab for the treatment of rheumatoid arthritis after failure of previous disease-modifying antirheumatic drugs.. HTA Ref: 08/118/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2012.
  
  
• The clinical and cost-effectiveness of different treatment pathways for neuropathic pain (NP). HTA Ref: 05/30/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Pazopanib for the first line treatment of patients with advanced and/or metastatic renal cell carcinoma: A Single Technology Appraisal. HTA Ref: 08/220/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2012.
  
  
• Managing Injuries of the Neck Trial (MINT). HTA Ref: 02/35/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Abiraterone acetate for the treatment of metastatic, castrate-resistant prostate cancer following previous cytotoxic chemotherapy. HTA Ref: 10/154/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Dasatinib and nilotinib for imatinib intolerant chronic myeloid leukaemia. HTA Ref: 08/31/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Boceprevir for the treatment of genotype 1 chronic hepatitis C. HTA Ref: 10/149/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Botulinum toxin type A for the prophylaxis of headaches in adults with chronic migraine. HTA Ref: 11/11/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Erlotinib for the first-line treatment of EGFR-TK mutation positive non-small-cell lung cancer. HTA Ref: 11/08/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Interactive group art therapy as an adjunctive treatment for people with schizophrenia (MATISSE). HTA Ref: 04/39/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Vinflunine for the second line treatment of transitional cell carcinoma of the urothelial tract. HTA Ref: 09/134/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2012.
  
  
• Assessing the effectiveness of Communication Therapy in the North West (the ACT NoW study). HTA Ref: 02/11/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease. HTA Ref: 09/62/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Telaprevir for the treatment of genotype 1 chronic hepatitis C. HTA Ref: 10/148/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Rituximab for the first-line maintenance treatment of follicular non-Hodgkin’s lymphoma. HTA Ref: 08/218/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2012.
  
  
• Comparison of culture tools with holistic evaluation of an organisation's culture. HTA Ref: 06/92/06.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: February 2012.
  
  
• The EndoVascular Aneurysm Repair (EVAR) trials 1 and 2: follow-up. HTA Ref: 95/02/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: February 2012.
  
  
• Bendamustine for chronic lymphocytic leukaemia. HTA Ref: 09/137/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2012.
  
  
• Rivaroxaban for the treatment of deep vein thrombosis and secondary prevention of venous thromboembolism.. HTA Ref: 10/85/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• Verteporfin photodynamic therapy cohort study for the UK. HTA Ref: 03/36/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• Dasatinib, high dose imatinib and nilotinib for the treatment of imatinib-resistant chronic myeloid leukaemia: a systematic review and economic evaluation (part review of Technology Appraisal No. 70). HTA Ref: 09/90/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) IBS (Intracranial Bleeding Study): The effect of tranexamic acid on intracranial bleeding among CRASH-2 trial participants. HTA Ref: 09/102/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• An evaluation of the feasibility, cost and value of information of a multicentre randomised controlled trial of intravenous immunoglobulin for sepsis (severe sepsis and septic shock). HTA Ref: 08/70/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• A pragmatic randomised controlled trial to evaluate exercise prescription as a treatment for depression (TREAD). HTA Ref: 03/45/07.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• Systematic review and validation of clinical prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care. HTA Ref: 07/37/05.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• What is the clinical and cost-effectiveness of using drugs in treating obese patients in primary care?. HTA Ref: 07/85/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: March 2012.
  
  
• Mode Of Data Elicitation, Acquisition and Response To Surveys (MODE ARTS). HTA Ref: 06/91/07.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Bevacizumab in combination with capecitabine for 1st line treatment of metastatic breast cancer. HTA Ref: 08/206/02.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Quantification of bias in randomised controlled trials and non-randomised studies: implications for systematic reviews and evidence synthesis (BRANDO study). HTA Ref: 06/91/10.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Dexamethasone for macular oedema (retinal vein occlusion). HTA Ref: 10/05/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2012.
  
  
• EOS low dose 2D/3D x-ray imaging system. HTA Ref: 10/67/01.
  Research Type: NICE Diagnostic Assessment.
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Donepezil, galantamine, rivastigmine and memantine for Alzheimer's (review of R111). HTA Ref: 09/87/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Mannitol dry powder for inhalation for the treatment of cystic fibrosis. HTA Ref: 09/41/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Management of frozen shoulder: a systematic review and decision analytic model. HTA Ref: 09/13/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Effectiveness of interventions to treat severely malnourished children. HTA Ref: 09/83/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Elucigene FH20 and LIPOchip for the diagnosis of familial hypercholesterolaemia. HTA Ref: 10/70/01.
  Research Type: NICE Diagnostic Assessment.
  Estimated date of publication in HTA journal series: April 2012.
  
  
• The clinical and cost effectiveness of Pharmalgen for the treatment of bee and wasp venom allergy. HTA Ref: 10/01/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: April 2012.
  
  
• A systematic review of prevention and intervention strategies for populations at high risk of engaging in violent behaviour: Update 2002-2007. HTA Ref: 08/101/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: April 2012.
  
  
• Birmingham And Lambeth Liver Evaluation Testing Strategies - BALLETS. HTA Ref: 03/38/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: May 2012.
  
  
• Assessment of Surgical sTaging versus Endobronchial and endoscopic ultrasound in lung cancer: a Randomised controlled trial (ASTER). HTA Ref: 06/302/216.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: May 2012.
  
  
• Outcomes of social care for adults: developing a preference weighted measure. HTA Ref: 06/96/01.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: May 2012.
  
  
• Ranibizumab for the treatment of diabetic macular oedema. HTA Ref: 10/21/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Optimal surveillance regimes for individuals with ocular hypertension (OHT): modelling and economic evaluation. HTA Ref: 07/46/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: May 2012.
  
  
• Pirfenidone for the treatment of idiopathic pulmonary fibrosis. HTA Ref: 09/135/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Computer and other electronic aids for smoking cessation. HTA Ref: 08/60/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Systematic review of head cooling in adults after traumatic brain injury and stroke. HTA Ref: 07/37/32.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Interventions to reduce or prevent obesity in pregnant women: A systematic review of evidence synthesis. HTA Ref: 09/27/06.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Ticagrelor for acute coronary syndromes. HTA Ref: 08/240/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Abatacept for the treatment of rheumatoid arthritis only after the failure of conventional DMARDs. HTA Ref: 10/24/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Rituximab for the first-line treatment of stage III-IV follicular lymphoma (Review of TA 110): systematic review and economic evaluation. HTA Ref: 09/141/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation. HTA Ref: 09/43/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Developing and testing methods for deriving preference-based measures of health from condition specific measures (and other patient based measures of outcome). HTA Ref: 06/97/04.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Home-based nursing health promotion for older people. HTA Ref: 09/142/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: June 2012.
  
  
• Modifying health promotion interventions to meet the needs of ethnic minority groups
  . HTA Ref: 07/63/03.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: July 2012.
  
  
• The clinical and cost-effectiveness of low-intensity psychological interventions for the secondary prevention of relapse after depression: a systematic review. HTA Ref: 09/67/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: July 2012.
  
  
• The clinical and cost-effectiveness of technologies used to visualise the seizure focus in people with refractory epilepsy being considered for surgery: a systematic review and decision analytical model. HTA Ref: 09/106/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: July 2012.
  
  
• The use of MElatonin in children with Neuro-Developmental disorders and impaired sleep; a randomised, double-blind, placebo-controlled, parallel Study (MENDS). HTA Ref: 05/14/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: July 2012.
  
  
• The measurement of patients' expectations for health care. HTA Ref: 07/58/01.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Gene expression profiling and expanded immunohistochemistry tests to guide the use of adjuvant chemotherapy in breast cancer management. HTA Ref: 10/125/01.
  Research Type: NICE Diagnostic Assessment Process (DAP).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Pre-operative testing: evidence synthesis, cost effectiveness and value of information analysis. HTA Ref: 06/84/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Screening for disorders of glucose regulation in cystic fibrosis. HTA Ref: 07/45/05.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Cost effectiveness of Transcatheter Aortic Valve Implantation (TAVI) for Aortic Stenosis in patients who cannot undergo surgery. HTA Ref: 10/110/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Colorectal cancer (metastatic) following the failure of first line chemotherapies - bevacizumab, cetuximab and (additionally) panitumumab (review of technology appraisal 150 and part-review of technology appraisal 118). HTA Ref: 10/11/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Systematic review and economic modelling of the relative clinical benefit and cost-effectiveness of laparoscopic surgery and robotic surgery for removal of the prostate in men with localised prostate cancer. HTA Ref: 09/14/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Cannabinoids (cannabis derivatives) for treatment of the symptoms of multiple sclerosis. HTA Ref: 02/23/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: Mid 2012.
  
  
• Computed tomography (CT) scanners for cardiac imaging – Somatom Definition Flash, Aquilion One, Brilliance iCT and Discovery CT750 HD. HTA Ref: 10/107/01.
  Research Type: NICE Diagnostic Assessment.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Bivalirudin for the treatment of ST-segment elevation myocardial infarction. HTA Ref: 10/09/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Clinical effectiveness of first-line chemoradiation for adult patients with locally advanced non-small cell lung cancer: A systematic review. HTA Ref: 09/126/02.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Non-pharmacological interventions to reduce the risk of diabetes in people with impaired glucose regulation: systematic review and economic evaluation. HTA Ref: 06/11/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Dasatinib, Nilotinib, and standard dose Imatinib for the first-line treatment of chronic myeloid leukaemia (including part review of TA70). HTA Ref: 08/226/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Retigabine for the adjunctive treatment of adults with partial onset seizures in epilepsy with and without secondary generalisation. HTA Ref: 10/51/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Primary stroke prevention in patients with sickle cell anaemia. HTA Ref: 10/14/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• Golimumab for the treatment of ankylosing spondylitis. HTA Ref: 08/205/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Mid 2012.
  
  
• Anaphylaxis: assessment to confirm an anaphylactic episode and the decision to refer after emergency treatment for a suspected anaphylactic episode.. HTA Ref: 10/158/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: August 2012.
  
  
• A pilot randomised control trial comparing seven days versus two days of empirical antibiotics to treat hospital acquired infection of unknown origin in intensive care patients. HTA Ref: 08/13/38.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: August 2012.
  
  
• The effectiveness and cost-effectiveness of acupressure for the control and management of chemotherapy-related acute and delayed nausea. (ANChoR: Acupressure and Nausea in ChemOtherapy Research trial). HTA Ref: 07/31/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Systematic review and meta-analysis of the current evidence on the duration of BCG protection. HTA Ref: 08/16/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Cancer of the oesophagus or gastricus: new assessment of the technology of endosonography (COGNATE). HTA Ref: 01/01/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Reminiscence groups for people with dementia and their family care-givers: pragmatic 8-centre trial of joint reminiscence and maintenance versus usual treatment. HTA Ref: 06/304/229.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: September 2012.
  
  
• The psychological consequences of false positive mammograms. HTA Ref: 09/145/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation: multicentre randomised controlled trial of antibiotic and antiseptic impregnated urethral catheters. HTA Ref: 05/46/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Generation of preference-based indices from DEMQOL and DEMQOL-PROXY for use in economic evaluation. HTA Ref: 07/73/01.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Management of Asthma in School-aged Children On Therapy - MASCOT. HTA Ref: 05/503/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: September 2012.
  
  
• Systematic review of the clinical effectiveness and cost-effectiveness, and economic evaluation, of denosumab for the treatment of bone metastases from solid tumours. HTA Ref: 08/236/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: October 2012.
  
  
• Eribulin for the treatment of locally advanced or metastatic breast cancer. HTA Ref: 10/19/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Evaluation of mammographic surveillance services in women under 50 with a family history of breast cancer (FH01). HTA Ref: 01/18/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: October 2012.
  
  
• Clinical and cost effectiveness of first-line chemotherapy for adult patients with locally advanced or metastatic non-small cell lung cancer: A systematic review and economic evaluation. HTA Ref: 09/126/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Fingolimod for relapsing or remitting multiple sclerosis. HTA Ref: 08/247/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• The place of minimal access surgery amongst people with gastro-oesophageal reflux disease - extended follow-up REFLUX-2. HTA Ref: 97/10/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: October 2012.
  
  
• Optimal strategies for monitoring kidney disease in diabetes: properties of monitoring tests, progression of renal dysfunction and impact of treatment. HTA Ref: 08/67/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: October 2012.
  
  
• Adjunctive colposcopy technologies for examination of the uterine cervix - Dysis, LuViva Advanced Cervical Scan, Niris Imaging System and APX 100. HTA Ref: 11/44/01.
  Research Type: NICE Diagnostic Assessment Process (DAP).
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Tocilizumab for the treatment of systemic juvenile idiopathic arthritis. HTA Ref: 07/70/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Echocardiography in newly diagnosed atrial fibrillation patients. HTA Ref: 08/45/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Development and validation of a risk model for identification of non-neutropenic, critically-ill, adult patients at high risk of invasive candida infection. HTA Ref: 07/29/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: November 2012.
  
  
• RCT to evaluate impact of diagnostic testing for influenza, respiratory syncytial virus and streptococcus pneumoniae infection on the management of acute admissions in the elderly. HTA Ref: 03/39/18.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: November 2012.
  
  
• Belimumab for the treatment of active autoantibody-positive systemic lupus erythematosus. HTA Ref: 10/73/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Fulvestrant for the treatment of locally advanced or metastatic breast cancer. HTA Ref: 09/129/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Cost-effectiveness of diagnostic strategies for suspected acute coronary syndrome (ACS). HTA Ref: 09/22/21.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: November 2012.
  
  
• Combined anticoagulation and antiplatelet therapy for high-risk patients with atrial fibrillation: systematic review and individual patient meta-analysis. HTA Ref: 09/11/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: November 2012.
  
  
• SonoVue® (sulphur hexafluoride microbubbles) - contrast agent for contrast enhanced ultrasound in liver imaging.. HTA Ref: 11/45/01.
  Research Type: NICE Diagnostic Assessment Process (DAP).
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Older People's Exercise intervention in Residential and nursing Accommodation (OPERA). HTA Ref: 06/02/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: November 2012.
  
  
• Natural History of Spinal Metastases. HTA Ref: 10/91/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: November 2012.
  
  
• Treatment of adult Attention Deficit Hyperactivity Disorder. HTA Ref: 11/16/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• HTA study of antidepressants for depression in dementia - a definitive multicentre pragmatic randomised controlled trial of clinical and cost effectiveness (HTA-SADD). HTA Ref: 04/11/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: November 2012.
  
  
• Ranibizumab for the treatment of macular oedema caused by retinal vein occlusion (RVO). HTA Ref: 09/132/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Screening for type 2 diabetes. HTA Ref: 11/18/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Colistimethate sodium powder for cystic fibrosis. HTA Ref: 10/08/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• UK home parenteral nutrition register. HTA Ref: 93/38/05.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• CT colonography, colonoscopy or barium enema for diagnosis of colorectal cancer in older symptomatic patients (SIGGAR1). HTA Ref: 02/02/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Roflumilast for chronic obstructive pulmonary disease.. HTA Ref: 10/06/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Telemonitoring or structured telephone support programmes for patients with severe heart failure. HTA Ref: 09/107/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Cabazitaxel for the second-line treatment of hormone refractory, metastatic prostate cancer. HTA Ref: 10/49/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Late 2012.
  
  
• Lithium or an atypical anti-psychotic in the management of treatment resistant depression: systematic review and economic evaluation. HTA Ref: 10/30/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• The cost effectiveness of fetal fibronectin (fFN) testing in suspected premature labour. HTA Ref: 10/130/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Depth of anaesthesia monitoring (E-Entropy, Bispectral Index and Narcotrend). HTA Ref: 11/57/01.
  Research Type: NICE Diagnostic Assessment Process (DAP).
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high risk groups.. HTA Ref: 09/15/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Late 2012.
  
  
• Long-acting exenatide for the treatment of type 2 diabetes. HTA Ref: 09/138/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2013.
  
  
• Ipilimumab for previously treated unresectable malignant melanoma. HTA Ref: 08/209/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2013.
  
  
• Omalizumab for the treatment of severe persistent allergic asthma. (Review of TA133 and TA201). HTA Ref: 10/128/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Clinical and cost-effectiveness of methods of managing varicose veins. HTA Ref: 10/29/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Apixaban for the prevention of venous thromboembolism in people undergoing elective knee and hip replacement surgery. HTA Ref: 09/124/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2013.
  
  
• SeHCAT (Tauroselcholic [75 selenium] acid) for the investigation of bile acid malabsorption (BAM) and measurement of bile acid pool loss. HTA Ref: 11/75/01.
  Research Type: NICE Diagnostic Assessment.
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for the treatment of osteoporotic vertebral fractures: a systematic review and cost-effectiveness analysis. HTA Ref: 10/122/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• A randomised trial of human papilloma virus testing in primary cervical screening (ARTISTIC). HTA Ref: 98/04/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: February 2013.
  
  
• Rivaroxaban for the prevention of stroke in atrial fibrillation. HTA Ref: 10/75/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated date of publication in HTA journal series in Supplement to the HTA journal series: Early 2013.
  
  
• A modelled analysis using data from the ARTISTIC trial of the potential effectiveness and cost-effectiveness of HPV testing in cervical cancer screening. HTA Ref: 09/66/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: March 2013.
  
  
• Folate Augmentation of Treatment - Evaluation for Depression: randomised controlled trial (FolATED). HTA Ref: 04/35/08.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• A longitudinal cohort study of people with lysosomal storage disorders. HTA Ref: 05/04/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• CRASH2 Trial, a large randomised placebo controlled trial among trauma patients with significant haemorrhage of the effects of an antifibrinolytic treatment on death and transfusion requirement. HTA Ref: 06/303/20.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• AMIPROM - A randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes. HTA Ref: 07/39/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Rapid systematic review of the impact of participation in research. HTA Ref: 08/249/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• RATPAC-CBE Randomised Assessment of Treatment using Panel Assay of Cardiac Markers - Contemporary Biomarker Evaluation. HTA Ref: 09/22/16.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Virus shedding and environmental deposition of novel A(H1N1) pandemic influenza virus - supplementary report. HTA Ref: 09/85/99.
  Research Type: Other types of research.
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• PRImary care Streptococcal Management study (PRISM). HTA Ref: 05/10/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Cost-effectiveness of diagnostic strategies for the management of abnormal uterine bleeding (heavy menstrual bleeding and post-menopausal bleeding): Systematic reviews, IPD meta-analysis and model based economic evaluation. HTA Ref: 09/63/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• MAGnesium NEbuliser Trial In Children (MAGNETIC). HTA Ref: 05/503/10.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Improving the value of screening for diabetic macular oedema using surrogate photographic markers. HTA Ref: 06/402/49.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Clinical Trials funded by the HTA Programme: specifying and extracting meta data. HTA Ref: 08/117/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Clinical effectiveness of PET-CT imaging in restaging recurrent cervical cancer: Systematic review of evidence and economic modelling. HTA Ref: 09/29/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• The diagnostic utility and cost-effectiveness of selective nerve root blocks in patients considered for lumbar decompression surgery: A systematic review and economic model. HTA Ref: 09/111/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Update and amalgamation of two Cochrane Reviews: neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
  . HTA Ref: 10/80/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• A multistranded study to determine the minimum cellularity required for the reliable assessment of Liquid Based Cervical (LBC) cytology samples. HTA Ref: 05/41/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Systematic review of the diagnostic accuracy and cost-effectiveness of magnetic resonance spectroscopy and enhanced magnetic resonance imaging techniques in aiding the localisation of prostate abnormalities for biopsy. HTA Ref: 09/146/01.
  Research Type: HTA Technology Assessment Report.
  Estimated date of publication in HTA journal series: Early 2013.
  
  
• Risk Adjustment In Neurocritical care (RAIN): prospective validation of risk prediction models for adult patients with acute traumatic brain injury to use to evaluate the optimum location and comparative costs of neurocritical care. HTA Ref: 07/37/29.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Systematic review and modelling of the cost effectiveness of Cardiac Magnetic Resonance Imaging compared to current existing testing pathways in cardiac disease. HTA Ref: 09/22/168.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• The clinical and cost effectiveness of ablative therapies in the management of liver metastases: systematic review and economic modelling study. HTA Ref: 09/79/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• A randomised controlled trial of different knee prostheses. HTA Ref: 95/10/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Assessing methods to specify the targeted difference for a randomised controlled trial. HTA Ref: 06/98/01.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Control of Hyperglycaemia in Paediatric intensive care trial (the CHIP trial). HTA Ref: 05/506/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• The effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care (AESOPS). HTA Ref: 06/304/142.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study. HTA Ref: 07/42/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• The growth and rupture rate of small abdominal aortic aneurysms: implications for population re-screening intervals. HTA Ref: 08/30/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• A multi-centre phase 3 cluster randomized controlled trial of a manualized anger management intervention for people with mild to moderate learning disabilities. HTA Ref: 08/53/34.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Allergen immunotherapy in adults and children with severe hay fever: systematic review of effectiveness and economic modelling. HTA Ref: 09/78/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Development and validation of a risk score for trauma patients with haemorrhage The CRASH-2 score. HTA Ref: 09/22/165.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Selective decontamination of the digestive tract in critically ill patients in Intensive Care Units (the SuDDICU study). HTA Ref: 09/01/13.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Sentinel lymph node (SLN) status in vulval cancer: Systematic quantitative reviews and decision analytic model based economic evaluation. HTA Ref: 09/112/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• The impact of continuous haemofiltration with high volume fluid exchange during cardiopulmonary bypass surgery on the recovery of patients with impaired renal function- A pilot study. HTA Ref: 08/53/33.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Community-based interventions for maintaining or improving quality of life in children and adolescents of parents with serious mental illness: An evidence synthesis. HTA Ref: 09/117/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Repeated measures analysis of data from the MS risk sharing scheme. HTA Ref: 10/55/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Exercise interventions for the management of health related quality of life and fatigue in cancer survivors during and after treatment
  . HTA Ref: 10/81/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• A natural history model of Chlamydia Trachomatis infection: incidence and prevalence of preventable complications. HTA Ref: 06/98/02.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: Mid 2013.
  
  
• Randomised controlled trial of tumour-necrosis-factor inhibitors against combination intensive therapy with conventional disease modifying anti-rheumatic drugs in established rheumatoid arthritis: the TACIT trial. HTA Ref: 06/303/84.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• A single blind randomised controlled trial to determine the effectiveness of group cognitive behaviour therapy (CBT) in the prevention of depression in high risk adolescents. HTA Ref: 06/37/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• The PLUTO Trial: Percutaneous shunting in Lower Urinary Tract Obstruction. HTA Ref: 07/01/44.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Care of older people who fall: evaluation of the clinical and cost effectiveness of new protocols for emergency ambulance personnel to assess and refer to appropriate community based care. HTA Ref: 07/01/21.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• A systematic review and economic evaluation of the effectiveness and generality of education interventions for preventing catheter-related bloodstream infections in critical care. HTA Ref: 09/01/25.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Enhancements to angioplasty for peripheral arterial occlusive disease (PAOD): systematic review, cost-effectiveness assessment and expected value of information analysis. HTA Ref: 09/116/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• A randomised controlled trial and cost-effectiveness evaluation of "booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods. HTA Ref: 07/25/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• An assessment of the cost-effectiveness of magnetic resonance including diffusion-weighted brain imaging in patients with transient ischaemic attack and minor stroke. HTA Ref: 09/22/169.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• A randomised controlled trial to investigate the clinical and cost effectiveness of adding an ablation device-based maze procedure as a routine adjunct to elective cardiac surgery for patients with pre-existing atrial fibrillation (AMAZE). HTA Ref: 07/01/34.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• COmparison of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: a Trial (CONSTRUCT). HTA Ref: 06/78/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Comparative study of new imaging technologies for the diagnosis of glaucoma. HTA Ref: 09/22/111.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Vitamin D supplementation in pregnancy: A systematic review. HTA Ref: 10/33/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Frequency of follow-up for patients with intermediate grade colorectal adenomas. HTA Ref: 04/33/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• The 3Mg Trial: Randomised controlled trial of intravenous or nebulised magnesium sulphate or standard therapy for acute severe asthma. HTA Ref: 06/01/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• A multicentre, randomised, placebo controlled trial of lactic acid bacteria in prevention of antibiotic-associated diarrhoea (AAD) & Clostridium difficile diarrhoea (CDD) in patients aged 65 years & over admitted to hospital and receiving antibiotics. HTA Ref: 06/39/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• First trimester progesterone therapy in women with a history of unexplained recurrent miscarriages: A randomised, double-blind, placebo-controlled, multi-centre trial [The PROMISE (PROgesterone in recurrent MIScarriage) Trial]. HTA Ref: 08/38/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Double-blind, randomised, placebo-controlled trial of nicotine replacement therapy (NRT) in pregnancy - SNAP. HTA Ref: 06/07/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2013.
  
  
• Bereavement and randomised controlled trials: a methodological study of policy and practice in neonatal and paediatric intensive care trials. HTA Ref: 05/516/06.
  Research Type: Methodology.
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• VenUS IV (Venous leg Ulcer Study IV): A randomised controlled trial of compression hosiery versus compression bandaging in the treatment of venous leg ulcers. HTA Ref: 07/60/26.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Using evidence to reduce risk of healthcare acquired infection following primary hip replacement. HTA Ref: 08/13/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Screening for the risk of self harm in an adult offender population. HTA Ref: 09/22/46.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Assessment of the feasibility and clinical value of further research to evaluate the management options for children with Down syndrome and otitis media. HTA Ref: 09/166/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• SARAH: Strengthening And stretching for people with Rheumatoid Arthritis of the Hands: The clinical and cost-effectiveness of an exercise programme over and above usual care. HTA Ref: 07/32/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• SLEEPS: Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation: a comparison of clonidine and midazolam. HTA Ref: 05/515/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Getting out of the house: a multi centre trial to evaluate an outdoor mobility intervention for people who have had a stroke. HTA Ref: 08/14/51.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• An exploratory trial to evaluate the effects of a physical activity intervention as a smoking cessation induction and cessation aid among the 'hard to reach'. HTA Ref: 07/78/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• United Kingdom Lung Cancer Screening Trial (UKLS) - Pilot. HTA Ref: 09/61/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• The management of otitis media with effusion (OME) in children with cleft palate: a feasibility study (MOMENT). HTA Ref: 09/167/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Supported self-management for patients with moderate to severe chronic obstructive pulmonary disease (COPD): an evidence synthesis and economic analysis. HTA Ref: 10/44/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Which children with otitis media with effusion benefit most from adenoidectomy with or without grommets (ventilation tubes)? An individual patient data meta-analysis. HTA Ref: 10/124/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Non pharmacological interventions for Attention-Deficit/Hyperactivity Disorder (ADHD) delivered in school settings: a systematic review of quantitative and qualitative research. HTA Ref: 10/140/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent (The FACS Trial). HTA Ref: 99/10/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• A randomised controlled trial (RCT) of alternative treatments to Inhibit VEGF in patients with Age-related choroidal Neovascularisation (IVAN). HTA Ref: 07/36/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Maximising engagement, motivation and long term change in a structured intensive education programme in diabetes for children, young people and their families: child and adolescent structured competencies approach to diabetes education. HTA Ref: 06/44/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• The Diagnosis of Urinary Tract infection in Young children (DUTY) study. HTA Ref: 08/66/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• INVESTIGATE - I (INVasive Evaluation before Surgical Treatment for Incontinence Gives Added Therapeutic Effect?): a pragmatic multicentre pilot study to assess the feasibility of a future randomised controlled trial. HTA Ref: 09/22/136.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• The clinical and cost effectiveness of diversion and aftercare programmes for offenders using class A drugs - a systematic review and economic model. HTA Ref: 09/109/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• The FAST (First-aid Advice & Safety Training) Parents programme for the prevention of recurrent unintentional home injuries in preschool children. HTA Ref: 09/02/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Systematic reviews and integrated report on the quantitative and qualitative evidence base for the management of obesity in men. HTA Ref: 09/127/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Systematic review to identify and appraise outcome measures used to evaluate childhood obesity treatment interventions: evidence of purpose, application, validity, reliability and sensitivity. HTA Ref: 09/127/07.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• The effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia. HTA Ref: 10/43/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• Screening for psychological and mental health difficulties of young people who offend: An integrated evidence synthesis and value of information analysis. HTA Ref: 10/35/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Early 2014.
  
  
• A randomised phase III trial of Docetaxel plus Prednisolone vs. Docetaxel with Prednisolone plus either Zoledronic acid, Strontium-89 or both agents combined (TRAPEZE). HTA Ref: 06/303/205.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: a randomised controlled trial. HTA Ref: 06/404/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• CATheter Infections in Children - the CATCH trial. HTA Ref: 08/13/47.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• TOMADO: crossover randomised controlled Trial of Oral Mandibular Advancement Devices for Obstructive sleep apnoea-hypopnoea. HTA Ref: 08/110/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• United Kingdom Oscillation Study: Long-term outcomes at follow up of two modes of neonatal ventilation. HTA Ref: 08/116/10.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• A pragmatic randomised controlled trial to evaluate the effectiveness and cost effectiveness of Collaborative cARE for people with DEMentia in primary care (CARE-DEM trial). HTA Ref: 08/53/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• INCLUSIVE trial: Initiating change locally in bullying and aggression through the school environment. HTA Ref: 09/05/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Feasibility study for a randomised controlled trial comparing hip arthroscopy with best conservative care for patients with femoro-acetabular impingement.. HTA Ref: 10/41/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• PERSEPHONE - duration of trastuzumab study with chemotherapy in early breast cancer: six versus twelve months. HTA Ref: 06/303/98.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Positron Emission Tomography-Computerised Tomography scans (PET-CT) guided watch and wait policy versus planned neck dissection for the management of locally advanced (N2/N3) nodal metastases in patients with head and neck squamous cancer. HTA Ref: 06/302/129.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• A randomised controlled trial of high frequency oscillatory ventilation in patients with acute respiratory distress syndrome (OSCAR). HTA Ref: 06/04/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• A randomised controlled trial of Outpatient Polyp Treatment (OPT) for abnormal uterine bleeding. HTA Ref: 06/404/84.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Cognitive-behavioural therapy for Health Anxiety in Medical Patients (CHAMP). HTA Ref: 07/01/26.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• The relative clinical and cost-effectiveness of three contrasting approaches to partner notification for curable sexually transmitted infections (STIs): a cluster randomised trial in primary care. HTA Ref: 07/43/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Can rapid integrated PolymeraseChain Reaction (PCR)-based diagnostics for gastrointestinal pathogens and direct sequence typing of clostridium difficile improve routine hospital infection control practice?. HTA Ref: 08/13/35.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• The impact of combined modality positron emission tomography with computerised tomography scanning (PET/CT) in the diagnosis and management of pancreatic cancer. HTA Ref: 08/29/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• An External Pilot Study to test the Feasibility of a Randomised Controlled Trial comparing Eye Muscle Surgery against Active Monitoring for Childhood Intermittent Distance Exotropia [X(T)]. HTA Ref: 09/01/20.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Alcohol misuse and sexual health: a randomised trial of brief intervention among people attending sexual health clinics. HTA Ref: 09/91/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Early parenting interventions for families with young children showing severe attachment problems: an integrated evidence synthesis. HTA Ref: 10/45/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• The clinical diagnostic validity of rapid detection of healthcare-associated blood stream infection in intensive care using multi-pathogen real-time polymerase chain reaction (RT-PCR) technology
  . HTA Ref: 08/13/16.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• The development of an algorithm to calculate in individual patients with abdominal aortic aneurysm (AAA) when repair is indicated to improve survival. HTA Ref: 09/91/39.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease. HTA Ref: 09/114/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• BIBS: Benefits of Incentives for Breastfeeding and Smoking cessation: A platform study for a trial. HTA Ref: 10/31/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• The cost effectiveness of genetic markers for antibiotic resistance in tuberculosis. HTA Ref: 10/96/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Smoking cessation for people with severe mental illness: a pilot study and definitive randomised evaluation of a bespoke service. HTA Ref: 07/41/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Early administration to preterm infants of the probiotic bifidobacterium breve strain BBG to prevent infection and necrotising enterocolitis. HTA Ref: 05/501/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Multi-centre cluster trial in primary care comparing a community group exercise programme with home based exercise and with usual care for people aged 65 and over. HTA Ref: 06/36/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• Randomised controlled trial comparing foam sclerotherapy, alone or in combination with endovenous laser therapy, with conventional surgery as a treatment for varicose veins. HTA Ref: 06/45/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• A systematic review of the diagnostic and prognostic utility of tests currently available for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease. HTA Ref: 10/36/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Mid 2014.
  
  
• A randomised controlled trial of continuous positive airway pressure treatment in older people with obstructive sleep apnoea hypopnoea syndrome (PREDICT). HTA Ref: 08/56/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Head Injury Transportation Straight to Neurosurgery (HITS-NS) trial - a feasibility study. HTA Ref: 08/116/85.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• A pilot study of the effectiveness and cost effectiveness of Multi-compartment Medication Devices.. HTA Ref: 09/34/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Therapeutic Communications in Black and Minority Ethnic Populations: a synthesis of the evidence base. HTA Ref: 10/141/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• The START (STrAtegies for RelaTives) study: a pragmatic randomised controlled trial to determine the effectiveness of a manual based coping strategy programme in promoting the mental health of carers of people with dementia. HTA Ref: 08/14/06.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• An evaluation of the effectiveness of ibuprofen and morphine for acute pain in sickle cell disease. HTA Ref: 07/48/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• A cluster randomised controlled trial of an occupational therapy intervention for residents with stroke living in UK care-homes. HTA Ref: 08/14/30.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Developing and piloting a peer mentoring intervention to reduce teenage pregnancy in looked after children and care leavers. HTA Ref: 08/20/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Bronchiolitis of Infancy Discharge Study (BIDS). HTA Ref: 09/91/16.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• ACTIvATeS: ACTive Treatment for Idiopathic AdolescenT Scoliosis - A feasibility study. HTA Ref: 10/38/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• A randomised controlled trial to compare the safety and effectiveness of doxycycline (200 mg/day) with prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid. HTA Ref: 06/403/51.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients - a cluster randomised controlled trial: FIAT (Financial Incentives for Adherence to Treatment). HTA Ref: 07/60/43.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Antibiotics for exacerbations of chronic obstructive pulmonary disease: a randomised trial within the General Practice Research Database. HTA Ref: 07/50/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Concordance in Diabetic Foot Ulceration. HTA Ref: 09/75/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• SABRE (hypertonic Saline in Acute Bronchiolitis Rct and Economic evaluation). HTA Ref: 09/91/22.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• Optimal strategies for monitoring lipid levels in patients at risk or with cardiovascular disease: best marker for monitoring and cost-effectiveness of different monitoring frequencies. HTA Ref: 10/97/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated date of publication in HTA journal series: Late 2014.
  
  
• The Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) Trial. HTA Ref: 06/43/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• The effectiveness and cost effectiveness of telephone triage of patients requesting same day consultations in general practice: a cluster randomised controlled trial comparing nurse-led and GP-led management systems. - The ESTEEM trial. HTA Ref: 08/53/15.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• A randomised, phase II trial in previously untreated patients with chronic lymphocytic leukaemia to compare fludarabine, cyclophosphamide and rituximab with fludarabine and cyclophosphamide, mitoxantrone and low dose rituximab. (CLL6). HTA Ref: 07/01/38.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• A multi-centre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and healthcare resource use following cardiac surgery (TITRe 2). HTA Ref: 06/402/94.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: multicentre placebo controlled randomised trial of calcium channel blockers (nifedipine) and alpha blockers (tamsulosin) - The SUSPEND trial. HTA Ref: 08/71/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• TOMMY trial: A comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme. HTA Ref: 09/22/182.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• CONtrol of Faecal Incontinence using Distal NeuromodulaTion (CONFIDeNT). HTA Ref: 09/104/16.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• Randomised controlled trial to assess the clinical- and cost-effectiveness of physiotherapy and occupational therapy in Parkinson's disease (PD REHAB). HTA Ref: 07/01/07.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• Probiotics for Antibiotic Associated Diarrhoea (including clostridium difficile) in care homes: establishing the platform and a randomised controlled trial (The PAAD Study). HTA Ref: 08/13/24.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• The role of ultrasound compared to biopsy of temporal arteries in the diagnosis and treatment of giant cell arteritis. HTA Ref: 08/64/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• A randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a displaced fracture of the distal radius. HTA Ref: 08/116/97.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• Anglo-Danish-Dutch study of Intensive Treatment of people with Newly diagnosed diabetes in primary care (ADDITION) - effects on cardiovascular events at five years. HTA Ref: 08/116/300.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• Accuracy of Bladder Ultrasound (BUS) in the diagnosis of Detrusor Overactivity (DO): a study to evaluate if ultrasound can reduce the need for urodynamics. HTA Ref: 09/22/122.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• The ProtecT trial - evaluating the effectiveness of treatments for clinically localised prostate cancer. HTA Ref: 96/20/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2015.
  
  
• Pragmatic multi-centre randomised trial of surgical versus non-surgical treatment for proximal fracture of the humerus in adults. HTA Ref: 06/404/53.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Surgical Trial In Traumatic intraCerebral Haemorrhage [STITCH). HTA Ref: 07/37/16.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• An international randomised controlled trial to compare targeted intra-operative radiotherapy (TARGIT) with conventional post-operative radiotherapy for women with early breast cancer. HTA Ref: 07/60/49.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Interferon gamma tests for the rapid identification of active tuberculosis disease. HTA Ref: 08/106/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Asymptomatic Carotid Surgery Trial-2 (ACST-2): an international randomised trial to compare carotid endarterectomy with carotid artery stenting to prevent stroke. HTA Ref: 06/301/233.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• CALORIES: A phase III, open, multicentre, randomised controlled trial comparing the clinical and cost-effectiveness of early nutritional support in critically ill patients via the parenteral versus the enteral route. HTA Ref: 07/52/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Protocolised Management In Sepsis (ProMISe): a multicentre, randomised controlled trial of the clinical and cost-effectiveness of early protocolised resuscitation for emerging septic shock. HTA Ref: 07/37/47.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Preventing depressive relapse in NHS Practice through mindfulness-based cognitive therapy (MBCT). HTA Ref: 08/56/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Amisulpride augmentation in clozapine-unresponsive schizophrenia (AMICUS). HTA Ref: 08/116/12.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• The CREAM Study - Children with Eczema, Antibiotic Management study. HTA Ref: 09/118/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Evaluating longer term outcomes of NHS stop smoking services. HTA Ref: 09/161/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• A pragmatic randomized controlled trial of physical activity as an aid to smoking cessation during pregnancy. HTA Ref: 07/01/14.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Observational study to estimate the changes in the efficacy of BCG with time since vaccination. HTA Ref: 08/17/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Development and validation of a Prediction model for Risk of complications in Early onset Pre eclampsia (PREP). HTA Ref: 09/22/163.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• A multicentre randomised controlled trial of an intelligent system to support decision making in the management of labour using the cardiotocogram (INFANT). HTA Ref: 06/38/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Collaborative care and active surveillance for screen-positive elders with sub-clinical depression: a pilot study and definitive and randomised evaluation - the CASPER trial. HTA Ref: 08/19/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• A randomised trial to increase the uptake of smoking cessation services using personal targeted risk information and taster sessions. HTA Ref: 08/58/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• A randomised controlled trial of self-help materials for the prevention of smoking relapse. HTA Ref: 09/91/36.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2015.
  
  
• Antidepressant Controlled Trial of Negative symptoms in Schizophrenia (ACTIONS). HTA Ref: 07/83/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• The clinical and cost-effectiveness of arthroscopic versus open surgical repair for tears of the rotator cuff (UKUFF trial). HTA Ref: 05/47/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• A randomised controlled trial of a protease inhibitor monotherapy versus continuing combination antiretroviral therapy for HIV-1 infected patients previously established on a dual nucleoside and non-nucleoside combination regimen. HTA Ref: 06/403/90.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Can emergency endovascular aneurysm repair (eEVAR) improves the survival from ruptured abdominal aortic aneurysm?. HTA Ref: 07/37/64.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• STeroids or Pentoxifyline for Alcoholic Hepatitis (STOPAH) Trial. HTA Ref: 08/14/44.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Individual Cognitive Stimulation Therapy for dementia (iCST Trial). HTA Ref: 08/116/06.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Cognitive behavioural therapy-based intervention to reduce fear of falling in older fallers attending a community falls service: Therapy development and randomised controlled trial. HTA Ref: 09/70/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Psychoeducation with problem solving (PEPS) therapy for adults with personality disorder: A community-based, randomised controlled trial. HTA Ref: 08/53/06.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Paediatric European Network for the Treatment of AIDS (PENTA)
  PENTA 16 Trial: Short-Cycle Therapy (SCT) (5 days on/2 days off) in young people with chronic HIV-infection. HTA Ref: 08/53/25.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• An open randomised study of autoinflation in school age children (4-11 years) with otitis media with effusion (OME) in primary care. HTA Ref: 09/01/27.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Effectiveness and Cost-effectiveness of Levonorgestrel containing Intrauterine system in Primary care against Standard trEatment - The ECLIPSE Trial. HTA Ref: 02/06/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• A multi-site randomized controlled trial comparing regional and general anaesthesia for effects on neurodevelopmental outcome and apnoea in infants. HTA Ref: 07/01/05.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• A randomised controlled trial of the LUCAS mechanical compression/decompression device for out of hospital cardiac arrest.. HTA Ref: 07/37/69.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• A study of position during the late stages of labour in women with an epidural. HTA Ref: 08/22/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• An evaluation of the effect of an angiotensin-converting enzyme (ACE) inhibitor on the growth rate of small abdominal aortic aneurysm. HTA Ref: 08/109/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• The CLOTS trial 3 (Clots in Legs Or sTockings after Stroke): a multicentre randomised trial to evaluate the effectiveness of Intermittent Pneumatic Compression (IPC) to prevent venous thromboembolism after stroke. HTA Ref: 08/14/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Can magnetic resonance imaging scan replace, or triage the use of laparoscopy in establishing diagnosis among women presenting in secondary care with chronic pelvic pain?. HTA Ref: 09/22/50.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• ASSSIST (Autism Spectrum Social Stories In Schools Trial). HTA Ref: 09/169/07.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Vitamin D and Longevity (ViDAL) trial - randomised feasibility study. HTA Ref: 08/116/48.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2015.
  
  
• Does home oxygen therapy (HOT) in addition to standard care improve disease severity and symptoms in chronic heart failure?. HTA Ref: 06/80/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• SHIFT. Self-Harm Intervention, Family Therapy: a randomised controlled trial of family therapy vs. treatment as usual for young people seen after second or subsequent episodes of self-harm. HTA Ref: 07/33/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Torpedo-CF: Trial of optimal therapy for pseudomonas eradication in cystic fibrosis. HTA Ref: 07/51/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• A randomised controlled trial evaluating the effectiveness and cost-effectiveness of Families for Health, a family-based childhood obesity management intervention delivered in a community setting for ages 7 to 11. HTA Ref: 09/127/41.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Comparison of close contact cast (CCC) technique to open surgical reduction and internal fixation (ORIF) in the treatment of unstable ankle fractures in patients over 60 years. HTA Ref: 07/37/61.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Positive Online WEight Reduction (POWER). HTA Ref: 09/127/19.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Prognostic value of interferon gamma release assays in predicting active tuberculosis among individuals with, or at risk of, latent tuberculosis infection. HTA Ref: 08/68/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Effectiveness and Cost-Effectiveness of Body Psychotherapy in the Treatment of Negative Symptoms of Schizophrenia. A multi-centre randomised controlled trial. HTA Ref: 08/116/68.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Randomised controlled trial of continuous subcutaneous insulin infusion compared to multiple daily injection regimens in children and young people at diagnosis of type I diabetes mellitus. HTA Ref: 08/14/39.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• A peer-support weight management programme to supplement brief advice in general practice for obese adults from deprived communities. HTA Ref: 09/127/34.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2016.
  
  
• Magnetic resonance imaging to enhance the diagnosis of fetal developmental brain abnormalities in utero. HTA Ref: 09/06/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• Antiepileptic drug (AED) management in Pregnancy: An evaluation of effectiveness, cost effectiveness and acceptability of dose adjustment strategies. HTA Ref: 09/55/38.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• A Randomised Controlled Trial In Patients With Respiratory Muscle Weakness Due to Motor Neurone Disease of the NeuRx RA/4 Diaphragm Pacing System (DiPALS). HTA Ref: 09/55/33.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• Seal or Varnish? A randomised trial to determine the relative cost and effectiveness of pit and fissure sealants and fluoride varnish in preventing dental decay. HTA Ref: 08/104/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• Randomised controlled trial of a pedometer-based walking intervention with and without practice nurse support in primary care patients aged 45-74 years. HTA Ref: 10/32/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• A randomised control trial to measure the effects and costs of a dental caries prevention regime for young children attending primary care dental services (Northern Ireland Caries Prevention In Practice Trial - NIC-PIP trial). HTA Ref: 08/14/19.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• Randomised controlled trial of brief psychodynamic psychotherapy, cognitive behaviour therapy and treatment as usual in adolescents with moderate to severe depression attending routine child and adolescent mental health clinics.. HTA Ref: 06/05/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• Randomised trial of a multifaceted podiatry intervention for fall prevention. HTA Ref: 09/77/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2016.
  
  
• The Stroke Oxygen Study (SO2S): A multi-centre, prospective, randomised, open, blinded-endpoint study to assess whether routine oxygen supplementation (ROS) in the first 72 hours after a stroke improves long-term outcome. HTA Ref: 09/104/21.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• A large randomised assessment of the relative cost-effectiveness of different classes of drugs for Parkinson's disease (PD MED). HTA Ref: 98/03/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• Clinical and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a Comprehensive Cohort Study. HTA Ref: 07/60/18.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• Weight Loss Maintenance in Adults: A 3 arm individually randomised controlled trial to evaluate the impact of a 12-month multi-component intervention and less intensive version compared to a control on weight loss maintenance in obese adults. HTA Ref: 08/44/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• Prevention of Falls Injury Trial. HTA Ref: 08/14/41.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• Obsessive Compulsive Treatment Efficacy Trial (OCTET). HTA Ref: 09/81/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• A pragmatic multicentre randomised controlled trial comparing stapled haemorrhoidopexy to conventional excisional surgery for haemorrhoidal disease.. HTA Ref: 08/24/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• A Study of Donor Ex-vivo Lung Perfusion in UK Lung Transplantation (DEVELOP-UK). HTA Ref: 10/82/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• Physical activity programmes for community dwelling people with mild to moderate dementia (DAPA - Dementia And Physical Activity). HTA Ref: 09/80/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2016.
  
  
• A cluster randomised controlled trial of the effectiveness and cost-effectiveness of an obesity prevention intervention in primary school age children. HTA Ref: 06/85/11.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Long-term tapering versus standard prednisolone (steroid) therapy for the treatment of the initial episode of childhood nephrotic syndrome: national multicentre randomised double blind controlled trial. HTA Ref: 08/53/31.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• An evaluation of multi-functional magnetic resonance imaging in the diagnosis and characterisation of prostate cancer. HTA Ref: 09/22/67.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Strategies to increase cervical screening uptake at first invitation (STRATEGIC). HTA Ref: 09/164/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• FIAT (Fistula-in-ano trial) comparing Surgisis® anal fistula plug versus surgeon's preference (advancement flap, fistulotomy, cutting seton) for transsphincteric fistula-in-ano. HTA Ref: 07/89/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• SWITCH - Randomised- controlled trial of switching to alternative tumour necrosis factor-blocking drugs or abatacept or rituximab in patients with rheumatoid arthritis who have failed an initial TNF-blocking drug. HTA Ref: 08/116/75.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Improving the prediction of metastatic disease in primary colorectal cancer: Prospective multicentre evaluation of a prognostic model of conventional predictive variables and novel variables derived from perfusion computed tomography (Perfusion CT). HTA Ref: 09/22/49.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Faecal immunochemical testing (FIT) for adenoma surveillance. FIT for Follow-up. HTA Ref: 09/22/192.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Randomised controlled trial of the clinical and cost-effectiveness of a contingency management intervention for reduction of cannabis use and of relapse in early psychosis. HTA Ref: 09/144/50.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Clopidogrel compared to Aspirin in Chronic HEart failure (CACHE). HTA Ref: 08/53/36.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• The REPOSE (Relative Effectiveness of Pumps Over MDI and Structured Education) Trial. HTA Ref: 08/107/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• Evaluation of lightweight fibreglass heel casts in the management of ulcers of the heel in diabetes. HTA Ref: 09/01/53.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• A practical randomised controlled double-blind trial of antipsychotic treatment of very late-onset schizophrenia-like psychosis: The ATLAS Trial. HTA Ref: 09/55/06.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2017.
  
  
• A controlled study of the effectiveness of breathing training exercises taught by a physiotherapist by either instructional videos/DVDs/internet download or by face-to-face sessions in the management of asthma in adults. HTA Ref: 09/104/19.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2017.
  
  
• COBRA (Cost and Outcome of BehaviouRal Activation): a Randomised Controlled Trial of Behavioural Activation versus Cognitive Behaviour Therapy for Depression. HTA Ref: 10/50/14.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2017.
  
  
• Improving the Quality of Dentistry (IQuaD): A randomised controlled trial comparing oral hygiene advice and periodontal instrumentation for the prevention and management of periodontal disease in dentate adults attending dental primary care. HTA Ref: 09/01/45.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2017.
  
  
• The Age of Blood Evaluation Study (ABLE). HTA Ref: 09/144/51.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2017.
  
  
• Tackling Early Morbidity and Mortality in Myeloma: Assessing the benefit of antibiotic prophylaxis and its effect on healthcare associated infections. HTA Ref: 08/116/69.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2017.
  
  
• FiCTION - Filling Children's Teeth: Indicated Or Not?. HTA Ref: 07/44/03.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2018.
  
  
• A trial to evaluate an extended rehabilitation service for stroke patients. HTA Ref: 10/37/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2018.
  
  
• Multicentre UK study of the acetylcholinesterase inhibitor donepezil in early dementia associated with Parkinson's disease (MUSTARDD-PD). HTA Ref: 08/14/13.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2018.
  
  
• INTERVAL Dental Recalls Trial [Investigation of NICE Technologies for Enabling Risk-Variable-Adjusted-Length Dental Recalls Trial] - Full Trial Follow-on. HTA Ref: 06/35/99.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2018.
  
  
• Plasma exchange and glucocorticoids in anti-neutrophil cytoplasm antibody associated systemic vasculitis: a randomized controlled trial. PEXIVAS. HTA Ref: 08/56/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2018.
  
  
• Phase III randomised controlled trial of the clinical effectiveness, safety and cost effectiveness of adalimumab for the treatment of juvenile idiopathic arthritis associated uveitis. HTA Ref: 09/51/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2018.
  
  
• Changing eating behaviours to treat childhood obesity in the community using Mandolean: the ComMando, (Community Mandolean) randomised trial.. HTA Ref: 09/127/04.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2018.
  
  
• The PRmotion Of Physical activity through structured Education with differing Levels of ongoing Support for those with prediabetes (PROPELS): randomised controlled trial in a diverse multi-ethnic community. HTA Ref: 09/162/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2019.
  
  
• FEMME trial: Randomised trial of treating Fibroids with either Embolisation or MyoMectomy to measure the Effect on quality of life. HTA Ref: 08/53/22.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2019.
  
  
• A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II). HTA Ref: 09/144/09.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2019.
  
  
• A randomised, multi-stage phase II/III study of Sunitinib comparing Temporary cessation with Allowing continuation, at the time of maximal response, in the first-line treatment of locally advanced/metastatic Renal cell carcinoma (the STAR trial). HTA Ref: 09/91/21.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2020.
  
  
• Total or Partial Knee Arthroplasty Trial (TOPKAT). HTA Ref: 08/14/08.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2020.
  
  
• BY-BAND. Gastric BYpass or adjustable gastric BANDing surgery to treat morbid obesity: a multi-centre randomised controlled trial. HTA Ref: 09/127/53.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Early 2021.
  
  
• Fast-Forward: a randomised clinical trial testing a 1-week course of curative whole breast radiotherapy against a standard 3-week schedule in terms of local cancer control and late adverse effects in women with early breast cancer. HTA Ref: 09/01/47.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Mid 2022.
  
  
• Randomised control trial of surveillance and no surveillance for patients with Barrett's oesophagus - BOSS (Barrett's Oesophagus Surveillance Study). HTA Ref: 05/12/01.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2024.
  
  
• SurgiCal Obesity Treatment Study (SCOTS). HTA Ref: 10/42/02.
  Research Type: Primary Research (e.g. trial).
  Estimated date of publication in HTA journal series: Late 2027.
  
  
• Translation of Spanish report on routine pre-operative testing. HTA Ref: 93/55/01.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
  
• Prostate trials office (PROTO): co-ordinating trials of new technologies in the treatment of BPH. HTA Ref: 94/04/05.
  Research Type: Methodology. No publication required.
  
  
• Funding to cover the costs incurred to hold the 4th International Balliol Surgical Trials Colloquia. Ref Professor Jonathan Meakins.. HTA Ref: 09/58/01.
  Research Type: Other types of research. No publication required.
  
  
• Development of the protocol for the proposed trial of beta interferon in multiple sclerosis. HTA Ref: 95/01/04.
  Research Type: Methodology. No publication required.
  
  
• Selective estrogen receptor modulators for osteoporosis. HTA Ref: 98/06/99.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
  
• Endovascular aortic aneurysm repair (EVAR) trials. HTA Ref: 95/02/02.
  Research Type: Primary Research (e.g. trial). No publication required.
  
  
• A systematic evaluation of the clinical and cost effectiveness of 'atypical' anti-psychotics in the treatment of schizophrenia. HTA Ref: 96/18/99.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
  
• Clinical and economic evaluation of hyaluronate membranes for prevention of complications of intra-abdominal adhesions. HTA Ref: 97/34/01.
  Research Type: Primary Research (e.g. trial). No publication required.
  
  
• Systematic review and economic modelling of the use of neuraminidase inhibitors for the prevention and treatment of influenza A and B. HTA Ref: 98/01/02.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
  
• Inhaler systems (devices) for childhood asthma. HTA Ref: 99/19/01.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
  
• The clinical and cost-effectiveness of trastuzumab and vinorelbine for breast cancer.. HTA Ref: 00/15/01.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
  
• A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent. HTA Ref: 99/10/09.
  Research Type: Primary Research (e.g. trial). No publication required.
  
  
• Taxanes (breast cancer): update. HTA Ref: 99/17/02.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
  
• Taxanes (ovarian cancer): update. HTA Ref: 99/17/03.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
  
• Update briefing paper on Positron Emission Tomography (PET) for cancer management. HTA Ref: 04/13/01.
  Research Type: Other types of research. No publication required.
  
  
• Antenatal screening for group B streptococcus colonisation - protocol development. HTA Ref: 05/05/01.
  Research Type: Methodology. No publication required.
  
  
• Prevention of colonisation with pseudomonas aeruginosa for cystic fibrosis patients. HTA Ref: 06/21/01.
  Research Type: Primary Research (e.g. trial). No publication required.
  
  
• The validity of aggregation methods in cost-utility analysis: what is the descriptive validity of the convention that "a QALY is a QALY is a QALY". HTA Ref: 06/90/01.
  Research Type: Methodology. No publication required.
  
  
• What is the value to society of a QALY? A proposal to write a protocol. HTA Ref: 06/90/02.
  Research Type: Methodology. No publication required.
  
  
• What is the value to society of a QALY: an investigation among the public in England and Wales. HTA Ref: 06/90/03.
  Research Type: Methodology. No publication required.
  
  
• Addressing ethnic diversity in health care outcome measurement. HTA Ref: 06/90/06.
  Research Type: Methodology. No publication required.
  
  
• Developing the Cochrane methodology register. HTA Ref: 06/90/07.
  Research Type: Methodology. No publication required.
  
  
• Evaluation of NICE guidance. HTA Ref: 06/90/08.
  Research Type: Methodology. No publication required.
  
  
• Scoping study on the assessment of the star ratings. HTA Ref: 06/90/09.
  Research Type: Methodology. No publication required.
  
  
• Informing the development of performance ratings. HTA Ref: 06/90/10.
  Research Type: Methodology. No publication required.
  
  
• Methods for identifying and classifying surgical site infection after discharge from hospital. HTA Ref: 06/90/14.
  Research Type: Methodology. No publication required.
  
  
• Evaluation of the Citizen's Council of NICE. HTA Ref: 06/90/15.
  Research Type: Methodology. No publication required.
  
  
• An update of two Cochrane reviews 'Peer reviewing for improving the quality of grant applications' and 'Editorial peer review for improving the quality of reports of biomedical studies'. HTA Ref: 06/90/17.
  Research Type: Methodology. No publication required.
  
  
• The value of a QALY implied by the value of a 'statistical life' in the field of transport. HTA Ref: 06/90/18.
  Research Type: Methodology. No publication required.
  
  
• Testing treatments on animals: relevance to humans. HTA Ref: 06/90/21.
  Research Type: Methodology. No publication required.
  
  
• A review of, and primary research into, approaches to the elicitation of individuals' (Bayesian) prior probabilities. HTA Ref: 06/91/01.
  Research Type: Methodology. No publication required.
  
  
• Enabling the Cochrane methodology register to serve the NHS R and D Methodology Group more effectively. HTA Ref: 06/91/03.
  Research Type: Methodology. No publication required.
  
  
• The relative societal value of health gains for different beneficiaries. HTA Ref: 06/91/04.
  Research Type: Methodology. No publication required.
  
  
• Satisfaction in Life for Children With Own Report Measures (SILCWORM). HTA Ref: 06/91/08.
  Research Type: Methodology. No publication required.
  
  
• Assessing and comparing mean costs of care in health economic evaluations based on clinical trials. HTA Ref: 06/91/09.
  Research Type: Methodology. No publication required.
  
  
• Developing an instrument to measure social inclusion - a literature review and consensus exercise (phase 1). HTA Ref: 06/91/12.
  Research Type: Methodology. No publication required.
  
  
• Infrastructure for guideline development. HTA Ref: 06/92/01.
  Research Type: Methodology. No publication required.
  
  
• What is the value to society of a QALY? An investigation among the public of England and Wales. HTA Ref: 06/90/04.
  Research Type: Methodology. No publication required.
  
  
• Missing data in randomised clinical trials. HTA Ref: 06/90/24.
  Research Type: Methodology. No publication required.
  
  
• Development of a "social inclusion index" to capture subjective and objective domains (phase 1). HTA Ref: 06/91/13.
  Research Type: Methodology. No publication required.
  
  
• A study to establish the feasibility of a trial that would investigate the clinical and cost-effectiveness of stopping bisphosphonate treatment after 5 years in post-menopausal women with osteoporosis who have already had a fracture. HTA Ref: 06/31/01.
  Research Type: HTA Technology Assessment Report. No publication required.
  
  
• A comparison and discussion of the methods, findings, adaptability and decisions resulting from two reviews of vision screening in children undertaken in the UK and Germany. HTA Ref: 05/52/02.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
  
• INTERVAL Dental recalls trial (Investigation of NICE Technologies for Enabling Risk-Variable-Adjusted-Length Dental Recalls Trial) - a feasibility study and follow on. HTA Ref: 06/35/05.
  Research Type: Primary Research (e.g. trial). No publication required.
  
  
• Lenalidomide for relapsed and/or refractory multiple myeloma. HTA Ref: 07/93/01.
  Research Type: NICE Evidence Review Group Report (ERG). No publication required.
  
  
• UK Lung Cancer Screening Trial (UKLS) - Feasibility study and protocol development. HTA Ref: 07/82/01.
  Research Type: Primary Research (e.g. trial). No publication required.
  
  
• Routine echocardiography in the management of stroke and TIA. HTA Ref: 09/68/01.
  Research Type: HTA Technology Assessment Report. No publication required.
  
  
• Bevacizumab (Avastin) for choroidal neovascularisation associated with wet age-related macular degeneration and other eye conditions: an assessment of the evidence base on clinical effectiveness and safety. HTA Ref: 10/48/01.
  Research Type: HTA Technology Assessment Report. No publication required.
  
  
• Bevacizumab in combination with non-taxane chemotherapy for the first-line treatment of metastatic breast cancer. HTA Ref: 08/206/01.
  Research Type: NICE Evidence Review Group Report (ERG). No publication required.
  
  
• Assessing the effectiveness of support for breastfeeding mothers: updating the Cochrane review. HTA Ref: 10/106/01.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
  
• Dutasteride for reducing the risk of developing prostate cancer. HTA Ref: 08/216/01.
  Research Type: NICE Evidence Review Group Report (ERG). No publication required.
  
  

Wed, 1 Feb 2012 15:33:28 +0000

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