Research type:
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Primary Research (e.g. trial) |
Title (lead author) etc:
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A 1-year follow-on study from a randomised, head-to-head, multicentre, open-label study of two pandemic influenza vaccines in children (de Whalley) 128 pages, Volume 15, number 45 |
DOI
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10.3310/hta15450 |
View/print executive summary
View/print abstract
View full text in pdf format (1872 KB)
Outputs from this project
- Walker, WT; de Whalley, P; Andrews, N; Oeser, C; Casey, M; Michaelis, L; Hoschler, K; Harrill, C; Moulsdale, P; Thompson, B; Jones, C; Chalk, J; Kerridge, S; John, T; Okike, I; Ladhani, S; Tomlinson, R; Heath, PT; Miller, E; Faust, SN; Snape, MD; Finn, A; Pollard, AJ.
H1N1 antibody persistence one year after immunisation with an adjuvanted or whole virion pandemic vaccine and immunogenicity and reactogenicity of subsequent seasonal influenza vaccine: a multi-centre follow-on study. Clinical Infectious Diseases 2012; 10.1093/cid/cir905.
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Headline: |
One year after immunisation, children receiving two doses of the routinely recommended, adjuvanted pandemic influenza vaccine had higher antibody levels than those receiving the alternative, egg-free vaccine; both groups produced a marked serological response to the H1N1 component of the 2010/11 seasonal influenza vaccine. |
This report should be referenced as follows: |
de Whalley P, Walker W, Snape M, Oeser C, Casey M, Moulsdale P, et al. A 1-year follow-on study from a randomised, head-to-head, multicentre, open-label study of two pandemic influenza vaccines in children. Health Technol Assess
2012;15(45).
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Project ref: |
10/111/01 |
Original project title: |
A 1-year follow-on study from a randomised, head-to-head, multicentre, open-label study of two pandemic influenza vaccines in children |
Chief Investigator: |
Professor Andrew Pollard, Professor of Paediatric Infection & Immunity,
Department of Paediatrics, University of Oxford
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Project Website |
http://www.paediatrics.ox.ac.uk/ovg/swineflu/ |
Start Date: |
November 2010 |
Date of publication in HTA journal series |
January 2012
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Cost: |
£350,626 |
Project Protocol: |
Project protocol (pdf format, 463 kbytes)
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Printed copies of this title despatched:
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111 (Figures relate to the previous calendar month) |
URL of this page: |
http://www.hta.ac.uk/2369 |