Research type:
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Primary Research (e.g. trial) |
Title (lead author) etc:
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A multi-centre retrospective cohort study comparing the efficacy, safety and cost-effectiveness of hysterectomy and uterine artery embolisation for the treatment of symptomatic uterine fibroids. The HOPEFUL study (Hirst) 248 pages, Volume 12, number 5 |
DOI
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10.3310/hta12050 |
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Headline: |
Study finds that uterine artery embolisation is an effective treatment for some women with fibroids and supports the NICE guidance that it should be made available as an option for treatment, possibly reducing the need for hysterectomy as the first-line treatment. |
This report should be referenced as follows: |
Hirst A, Dutton S, Wu O, Briggs A, Edwards C, Waldenmaier L, et al. A multi-centre retrospective cohort study comparing the efficacy, safety and cost-effectiveness of hysterectomy and uterine artery embolisation for the treatment of symptomatic uterine fibroids. The HOPEFUL study. Health Technol Assess
2008;12(5).
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Project ref: |
03/60/01 |
Original project title: |
Treatment for fibroids: Uterine Artery Embolisation (UAE) or hysterectomy (HOPEFUL) |
Chief Investigator: |
Professor Klim McPherson, Visiting Professor of Public Health Epidemiology,
Nuffield Dept of Obstetrics and Gynaecology, University of Oxford
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Start Date: |
December 2003 |
Date of publication in HTA journal series |
March 2008
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Cost: |
£567,611 |
MeSH* index primary terms: |
LEIOMYOMA Q-therapy; EMBOLIZATION-THERAPEUTIC Q-methods; HYSTERECTOMY Q-methods; PATIENT-SATISFACTION (* = Medical Subject Headings) |
MeSH* index secondary terms: |
HUMAN; FEMALE; RECURRENCE; RISK-FACTORS; COST-BENEFIT-ANALYSIS; FEASIBILITY-STUDIES; RETROSPECTIVE-STUDIES; COHORT-STUDIES; COMPARATIVE-STUDY; QUALITY-OF-LIFE; QUESTIONNAIRES; SURVIVAL-ANALYSIS (* = Medical Subject Headings) |
NRR* number, if applicable: |
N0484135403 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive. |
Project Protocol: |
Project protocol (pdf format, 223 kbytes)
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Printed copies of this title despatched:
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106 (Figures relate to the previous calendar month) |
Downloads/Views of electronic version from website:
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29491 (Figures
are cumulative.) Last updated 27th July 2010. |
URL of this page: |
http://www.hta.ac.uk/1382 |
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