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Details of HTA journal title

Research type:

 Primary Research (e.g. trial) 

Title (lead author) etc:

 A multi-centre retrospective cohort study comparing the efficacy, safety and cost-effectiveness of hysterectomy and uterine artery embolisation for the treatment of symptomatic uterine fibroids. The HOPEFUL study  (Hirst) 248 pages, Volume 12, number 5

DOI

 10.3310/hta12050
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Outputs from this project



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Headline:

 Study finds that uterine artery embolisation is an effective treatment for some women with fibroids and supports the NICE guidance that it should be made available as an option for treatment, possibly reducing the need for hysterectomy as the first-line treatment. 

This report should be referenced as follows:

 Hirst A, Dutton S, Wu O, Briggs A, Edwards C, Waldenmaier L, et al. A multi-centre retrospective cohort study comparing the efficacy, safety and cost-effectiveness of hysterectomy and uterine artery embolisation for the treatment of symptomatic uterine fibroids. The HOPEFUL study. Health Technol Assess 2008;12(5).

Project ref:

 03/60/01 

Original project title:

 Treatment for fibroids: Uterine Artery Embolisation (UAE) or hysterectomy (HOPEFUL) 

Chief Investigator:

 Professor Klim McPherson, Visiting Professor of Public Health Epidemiology, Nuffield Dept of Obstetrics and Gynaecology, University of Oxford

Start Date:

 December 2003  

Date of publication in HTA journal series

 March 2008

Cost:

 £567,611 

MeSH* index primary terms:

 LEIOMYOMA Q-therapy; EMBOLIZATION-THERAPEUTIC Q-methods; HYSTERECTOMY Q-methods; PATIENT-SATISFACTION (* = Medical Subject Headings)

MeSH* index secondary terms:

 HUMAN; FEMALE; RECURRENCE; RISK-FACTORS; COST-BENEFIT-ANALYSIS; FEASIBILITY-STUDIES; RETROSPECTIVE-STUDIES; COHORT-STUDIES; COMPARATIVE-STUDY; QUALITY-OF-LIFE; QUESTIONNAIRES; SURVIVAL-ANALYSIS  (* = Medical Subject Headings)

NRR* number, if applicable:

 N0484135403 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive.

Project Protocol:

 Project protocol (pdf format, 223 kbytes)

Printed copies of this title despatched:

 106 (Figures relate to the previous calendar month)

URL of this page:

http://www.hta.ac.uk/1382
Last updated: 1 February 2012 - Next update due: 8 February 2012

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