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Details of HTA published project

Research type:	Secondary Research (e.g. systematic review)
Title (lead author) etc:	Measurement of the clinical and cost-effectiveness of non-invasive diagnostic testing strategies for deep vein thrombosis (Goodacre) 168 pages, Volume 10, number 15
DOI	10.3310/hta10150
This publication is now a part of the NIHR Journals Library. Documents relating to the publication can be found at the corresponding journal issue page, which is at the following link: http://www.journalslibrary.nihr.ac.uk/hta/volume-10/issue-15 Outputs from this project Goodacre, S; Sampson, F; Thomas, S; van, Beek E; Sutton, A. Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis. Biomed Central Medical Imaging 2005; 5(6). Goodacre, S; Sampson, FC; Sutton, AJ; Mason, S; Morris, F. Variation in the diagnostic performance of D-dimer for supected deep vein thrombosis. Quarterly Journal of Medicine 2005; 98(7): 513-527. Goodacre, S; Sutton, AJ; Sampson, FC,. Meta-analysis: the value of clinical assessment in the diagnosis of deep vein thrombosis. Annals of Internal Medicine 2005; 143(2):129-139. Sampson, F; Goodacre, S; Kelly, AM; Kerr, D. How is deep vein thrombosis diagnosed and managed in UK and Australian emergency departments?. Emergency Medicine Journal 2005; 22(11):780-782. Goodacre, S; Stevenson, M; Wailoo, A; Sampson, F; Sutton, AJ; Thomas, S. How should we diagnose suspected deep-vein thrombosis. Quarterly Journal of Medicine 2006; 99(6):377-388. Locker, T; Goodacre, S; Sampson, F; Webster, A; Sutton, AJ. Meta-analysis of plethysmography and rheography in the diagnosis of deep vein thrombosis. Emergency Medicine Journal 2006; 23(8): 630-635. Sampson, F; Goodacre, S; Thomas, S; van Beek, E. The accuracy of MRI in diagnosis of suspected deep vein thrombosis: systematic review and meta-analysis. European Radiology (2007) 17(1):175-181.
Headline:	Investigations into non-invasive tests for deep vein thrombosis (DVT) found that using combined diagnostic tools that included Wells score, D-dimer and ultrasound (with repeat if negative) was feasible at most UK hospitals and was more cost-effective than radiological testing for all patients.
This report should be referenced as follows:	Goodacre S, Sampson F, Stevenson M, Wailoo A, Sutton A, et al. Measurement of the clinical and cost-effectiveness of non-invasive diagnostic testing strategies for deep vein thrombosis. Health Technol Assess 2006;10(15).
Project ref:	02/03/01
Original project title:	Measurement of the clinical and cost effectiveness of non invasive diagnostic testing strategies for deep vein thrombosis
Chief Investigator:	Professor Steve Goodacre, Professor of Emergency Medicine, School of Health and Related Research (ScHARR), University of Sheffield
Start Date:	April 2003
Date of publication in HTA journal series (now NIHR Journals Library)	May 2006
Cost:	£114,655
MeSH* index primary terms:	VENOUS-THROMBOSIS Q-diagnosis (* = Medical Subject Headings)
MeSH* index secondary terms:	HUMAN; REVIEW-ACADEMIC; COST-BENEFIT-ANALYSIS; QUALITY-OF-LIFE (* = Medical Subject Headings)
NRR* number, if applicable:	N0484121627 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive.
Project Protocol:	Project protocol not available
URL of this page:	http://www.hta.ac.uk/1340

Last updated: 18 June 2013 - Next update due: 25 June 2013

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