Direct link to this page: http://www.hta.ac.uk/1270

Details of HTA journal title

Last updated: 31 August 2010 - Next update due: 7 September 2010

Research type:

Secondary Research (e.g. systematic review) 

Title (lead author) etc:

Screening for thrombophilia in high-risk situations: systematic review and cost-effectiveness analysis. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study  (Wu) 110 pages, Volume 10, number 11

DOI

10.3310/hta10110
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Outputs in journals arising from this project

Headline:

Study shows that significant risks for venous thromboembolism (VTE) and adverse pregnancy outcomes have been established with individual thrombophilic defects. Selective screening for thrombophilia based on prior VTE history was found to be more cost-effective than universal screening. 

Project ref:

01/04/03 

Original project title:

Screening for thrombophilia: benefits, risks and cost-effectiveness 

Chief Investigator:

Professor Ian Andrew Greer, Deputy Dean and Head of Department, Reproductive and Maternal Medicine, Glasgow Royal Infirmary

Start Date:

July 2002  

Date of publication in HTA journal series

April 2006

Cost:

£119,211 

MeSH* index primary terms:

THROMBOPHILIA Q-prevention-&-control; MASS-SCREENING Q-methods (* = Medical Subject Headings)

MeSH* index secondary terms:

HUMAN; RETROSPECTIVE-STUDIES; RISK-FACTORS; MASS-SCREENING Q-economics; COST-BENEFIT-ANALYSIS; REVIEW-ACADEMIC  (* = Medical Subject Headings)

NRR* number, if applicable:

N0484107818 (*National Research Register) The National Research Register was a public database of ongoing and recently completed research projects funded by, or of interest to, the United Kingdom's National Health Service (NHS). It is now an archive of projects from early 2000 to September 2007. Search the NRR archive.

Project Protocol:

Project protocol not available

Printed copies of this title despatched:

121 (Figures relate to the previous calendar month)

Downloads/Views of electronic version from website:

37671 (Figures are cumulative.) Last updated 27th July 2010.

URL of this page:

http://www.hta.ac.uk/1270

Outputs from this project

  • Wu, O; Robertson, L; Langhorne, P; Twaddle, S; Lowe, GDO; Clark, P; Greaves, M; Walker, ID; Brenkel, I; Regan, L; Greer, IA. Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thromb Haemost. 2005 Jul;94(1):17-25.
  • Wu, O; Robertson, L; Twaddle, S; Lowe, GDO; Clark, P; Walker, I; Brenkel, I; Greaves, M. Screening for thrombophilia in high-risk situations: a meta-analysis and cost-effectiveness analysis. Br J Haematol. 2005 Oct;131(1):80-90.
  • Robertson, L; Wu, O; Langhorne, P; Twaddle, S; Clark, P; Lowe, GDO; Walker, ID; Greaves, M; Brenkel, I; Regan, L; Greer, IA. Thrombophilia in pregnancy: a systematic review. Br J Haematol. 2006 Jan;132(2):171-96.
Tue, 31 Aug 2010 16:14:10 +0100

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